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Azure high-performance computing

Unlock your innovation with the leading HPC cloud solution.


Azure high-performance computing (HPC) is a complete set of computing, networking, and storage resources integrated with workload orchestration services for HPC applications. With purpose-built HPC infrastructure, solutions, and optimized application services, Azure offers competitive price/performance compared to on-premises options. with additional high-performance computing benefits. Additionally, Azure includes next-generation machine-learning tools to drive smarter simulations and empower intelligent decision making.

  • Optimized performance with cost control

    Maximize the full range of CPU, GPU, FPGA, and fast interconnect capabilities to reduce job completion times from days to minutes.

  • End-to-end workflow agility

    Build and manage HPC clusters for your own exclusive use, enabling end-to-end application lifecycle management in the cloud.

  • Production-class platform

    With robust HPC reliability, data security, and global regulatory compliance, Azure is the cloud that just works.

  • Incorporating intelligence

    Build and train new AI models faster with automated machine learning, autoscaling cloud compute, and built-in DevOps.

Duke University ventilator splitting project

Ventilators have become a scarce resource during the COVID-19 pandemic. Professor Randles and her team at Duke University rushed to find a safe and easy way to effectively split a single ventilator between two patients. They partnered with Microsoft AI for Health to run more than 800,000 computer hours in just 36 hours to build a life-saving solution.

Explore Azure HPC solutions by application and industry

Empower developers, engineers, scientists, and researchers to make new breakthroughs in their fields with Azure HPC.

Azure Synapse Analytics


Simulate all aspects of vehicle engineering cost-effectively and at scale with highly secure infrastructure.

Azure Databricks

Financial services

Confidently meet regulatory requirements with an elastic and intelligent infrastructure for risk modeling. Extend your capacity as needed and pay for only what you use.

Azure Machine Learning


Optimize all stages of upstream oil and gas industry exploration, appraisal, completion, and production.

Power BI

Health and life sciences

Accelerate insights in genomics, precision medicine, and clinical trials with near-infinite high-performance bioinformatics infrastructure.

Microsoft Purview


Scalable, secure, on-demand, high-performance infrastructure with compute, storage, and networking optimized for electronic design automation (EDA) workloads.

Azure Data Lake Storage


Rapidly iterate on product design to reduce time to market and improve product quality with scalable and highly secure on-demand HPC infrastructure.


Machine learning

Get powerful remote workstations, run clusters with near-infinite scale, and gain better insights with advanced analytics, machine learning, and AI workloads running on Azure.

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Run any graphic-intensive workload in the cloud and deliver extraordinary experiences to any device, anywhere, anytime, with Azure’s 50+ global datacenter regions.

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Render with confidence on a scalable, MPAA-certified, non-competing platform that’s trusted by 95 percent of the Fortune 500.

HPC platform services

Get vast compute resources with a cloud platform built for global scale and outfitted with services specifically geared toward HPC workloads.


Establish private, secure tunnels for hybrid cloud connectivity using Azure ExpressRoute. Take advantage of Linux remote direct memory access (RDMA) with InfiniBand for message passing interface (MPI) workloads within your datacenter.


Find the right high-performance computing resources at nearly unlimited scale on Azure. Use H-series virtual machines for memory-bound applications, N-series virtual machines for graphic intensive and CUDA/OpenCL based applications, or Cray for a fully dedicated and customized supercomputer delivered as a managed service.


Burst your HPC applications into Azure using data stored in on-premises NAS devices with HPC Cache. Access large amounts of I/O with a sub-millisecond latency with Azure NetApp Files, delivered as an Azure service natively within an Azure datacenter. For a high throughput storage solution, use Cray ClusterSor, a Lustre-based, bare-metal HPC storage solution that’s fully integrated with Azure.

Application Services

Create and manage applications and schedule jobs with Azure Batch. Dynamically provision Azure HPC clusters with Azure CycleCloud.

Intelligent Services

Build the next generation of applications with predictive analysis using Data Lake Analytics. Gain insights that lead to better decisions by building and running machine learning models on top of your HPC data.

Azure HPC Overview

Azure HPC purpose-built infrastructure and optimized application services.

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Fully managed supercomputing service on Azure

  • Get a dedicated, fully managed, single-tenant Cray XC or CS series supercomputer. Take advantage of Cray ClusterStor high-performance storage in Azure or with Azure H-series virtual machines. Features include:

  • Dedicated, customized, fully managed supercomputers.

  • Single tenancy on bare metal for complete control and privacy over your computing environment.

  • No data movement—your data stays on the same Azure network as your RDMA, GPU, or FPGA virtual machines.

  • Transformative services such as AI, deep learning, and advanced analytics.